Neurobiology of Memory Reconsolidation

Neurobiology of Memory Reconsolidation What is the current understanding of the neurobiology of memory reconsolidation and how will impact psychology. Abstract This essay is focusing on the neurobiology of memory reconsolidation, specifically on the molecular mechanisms of LTP and reconsolidation, and the crucial role synaptic plasticity plays in fear conditioning and its resultant implication for psychopathology specifically Posttraumatic stress disorder This essay is focusing on current understanding of the neurobiology of memory reconsolidation, specifically on the molecular mechanisms of LTP and reconsolidation, and its resultant implication for psychopathology specifically promising research using propranolol and d-cycloserine as a treatment of post-traumatic stress disorder. Memory consolidationis the process by which memories are stabilised after being acquired. Consolidation studies have traditionally focused on the hippocampus andsystems consolidation, whereshort term memories become long term memories and independent of thehippocampus over time (Pinel, 2011). The more recently discovered process of consolidation is synaptic consolidation, which occurs within the first few hours after learning, and requires protein synthesis and gene transcription (Pinel, 2011). Long term memories were once considered to be stable, but within the last decade, the discovery of reconsolidation, the process in which stored memories can be retrieved and held in labile short-term memory, has changed theory and research on memory (Pinel, 2011). The neurobiological process of synaptic memory consolidation is thought to be long-term potentiation (LTP), which is the prolonged strengthening of the synapse with increased signalling between two neurons (Sacktor, 2012). The model of LTP and synaptic consolidation, as first theorised by Hebb (Pinel, 2011), suggests that changes in membrane potential and alterations of synapticprotein synthesis such as activating Phosporylated Mitogen Activated Protein Kinase (MAPK),are achieved through activatingintracellular transduction cascades, such as glutamate activating the NMDA receptor so that calcium ions can enter the neuron. These molecular cascades triggertranscription factors such as CREBthat lead to changes ingene expression through RNA synthesis (Pinel, 2011). The result of the gene expression is the lasting structural remodelling of synapses. This complex process of the molecular cascade, expression and process of transcription factors, is susceptible to disruptions in the short ti me period immediately following memory induction (Nader, Schafe LeDoux, 2000a). The potential for memory to be distrupted during consolidation has been extensively researched using pharmacology and trauma. For example, in experiments on Pavlovian fear conditioning in rats, LTP and fear conditioning were blocked when NMDA-receptorantagonistswere administered (Nader et al, 2000b). This process ofLTPis regarded as a contributing factor tosynaptic plasticityand in the growth ofsynaptic strength, and is thought to underlie memory formation, as it affects memory when disrupted. It was previously thought that even though this long process of consolidation could be disrupted, once a memory was consolidated it could not be disrupted. This classic view has been revised over the last 15 years, with extensive research showing that consolidated memories, once retrieved, revert to a labile state where they can be disrupted and undergo another consolidation process, called reconsolidation. (Shwabe, 2014). Reconsolidation was first hypothesised after studies were done using electroconvulsive shock therapy to disrupt consolidated fear memory (Tronson Taylor, 2007). Nader’s (2000a) landmark research using Pavlovianfear conditioningon rats found that a consolidated fear memory can return to alabilestate, when the amygdalais infused with theprotein synthesis inhibitor anisomycin. Subsequent studies have also shown that post-retrieval treatment with protein synthesis inhibitors can lead to an amnestic state (Shwabe, 2014). It has been concluded therefore that cons olidated fear memory, when reactivated, enters a changeable state that requires de novo protein synthesisfor new consolidation or reconsolidation of the old memory (Shwabe, 2014). Since these breakthrough studies many more have found evidence supporting reconsolidation, and have explored its processes and implications. Reconsolidation research over the last decade has demonstrated that some, but not all memories can be strengthened, weakened, or updated thus providing an opportunity to modify some long term memories (Shwabe, 2014). This very limited essay will focus on a few of the important animal and human studies related to fear memory and reconsolidation theory and its implications for psychology. Fear conditioning, fear memory and extinction learning experiments, often use manipulations of theamygdala, due to its involvement in the encoding and memory of significant emotional experiences (Agren et al, 2012). Most of the research on reconsolidation has been done on animals, one of the first studies of human fear memory consolidation was by Kindt in 2009 in which healthy participants were first fear-conditioned and the fear was reactivated by a single presentation of a conditioned stimulus 24 hours later. Shortly before memory reactivation, participants received the beta-adrenergic receptor blocker propranolol during the proposed reconsolidation window, which resulted in substantial weakening of the behavioural fear response and the return of fear memory. Research by Schiller (2010) also explored fear memory activation and update mechanisms and extinction learning, and found the ventromedial prefrontal cortex (vmPFC) plays an important role (Schiller, 2013). Agren et al (2012) also demonstrated fear memory trace erasure in the amygdala of humans using behavioural manipulations. Using functional brain imaging, Agren and colleagues (2012) found that when reconsolidation was disrupted through extinction training, the fear memory was significantly weakened and the memory trace was erased in the amygdala. Additional important recent research providing support for memory updating used Pavlovian fear conditioning manipulations and micro density heat map measures of fear memory on the lateral amygdala of rats, and found that the memory recapitulated not only in the same location but in new areas during reconsolidation (Bergstrom, McDonald, Dey, Tang, Selwyn Johnson, 2013). These, and many more important studies using different experimental manipulations, suggest that memory is labile and updated after reactivation, and that more or less the same areas are recruited for reconsolidation that are involved in initial memory formation. The potential ability to modify established emotional memories through the processes of memory updating, reconsolidationand extinction of conditioned fear memories has important implications for the treatment of many mental disorders, including anxiety disorders, such as post-traumatic stress disorder. Posttraumatic stress disorder is classified as ananxiety disorderin the DSM iV, characteristic symptoms of PTSD are strong traumatic memories that are continuously retrieved in an intrusive manner, causing re-experiencing of the original trauma (Schwabe, 2014).Research is focusing on testing pharmacological treatments and behavioural interventions that target memory reconsolidation in PTSD populations. One drug being researched in neurobiology for the treatment of PTSD is propranolol, the b-adrenergic receptor antagonist that has effects on protein synthesis. The idea that propranolol could be a useful treatment in PTSD stemmed from studies showing that this drug can disrupt the reconsolidation of fear conditioning in animal models and humans (Kindt, 2009). There is some evidence of success with propranolol, such as in pilot studies by Pitman (2002) and Vaiva (2003) which found that immediate treatment with propranolol decreases posttraumatic stress disorder two months after trauma. In recent experiments using propranolol, patients with chronic PTSD were asked to prepare a written script of their personal traumatic experience that caused the PTSD. Each patient then received either propranolol or a placebo (Brunet et al, 2008). One week later, all patients underwent a procedure where there physiological arousal was tested as the script was read. The results showed that psychophysiological responding was significantly lower in patients who had received propranolol a week earlier than in patients who were administered a placebo. These findings were replicated and extended in three open-label studies where PTSD symptoms were significantly lower than at pretreatment (Brunet et al, 2011). In these promising studies on the effect of post-retrieval propranolol in chronic PTSD it is ambiguous as to whether the benefits were from propranolol enhancement or the psychological intervention; And whether propranolol enhanced extinction consolidation or blocked memory reconsoli dation. (de Kleine et al, 2013). Some of these studies also lacked the appropriate control groups that would be required to conclude that the observed effects are due to changes in memory reconsolidation, however, these findings suggest that postretrieval manipulations with propranolol might be a promising tool in the treatment of PTSD, even when the trauma is decades old. d-cycloserine (DCS) is another pharmacological intervention being recently researched in reconsolidation and PTSD due to it being a partial NMDA receptor agonist and extinction enhancer (De Kliene, 2014). Research on using exposure therapy with DCS for PTSD suggests that it could be promising (De Kliene, 2014). Exposure therapy is established as an effective form of fear extinction training in PTSD through the repeated exposure of the trauma memory, and its emotional processing (De Kliene, 2014). De Kleine, Hendriks, Kusters, Broekman, and van Minnen (2012) investigated the effect of DCS on exposure therapy on a female civilian population and found no overall enhancement effects, but a stronger treatment response. However, a second study on a male veteran population found a significant enhancement (Litz et al, 2012). Some criticisms of these studies were the possibility that DCS might have undesirable effects when there is no in session fear extinction, and the need for more research and better administration of the drug (De Kleine, 2014). Sheeringa (2014) researched the effect of d-cycloserine with cognitive behaviour therapy on pediatric posttraumatic stress using a randomized placebo-controlled d-cycloserine. So far, DCS has only shown as extinction effect when used with behavioural training such as exposure therapy and CBT. This study did not show a greater effect on reducing PTSD symptoms, but did show preliminary evidence for improving attention of participants. Another promising study currently in press looked at whether DCS enhanced psychotherapy when used with virtual reality trauma exposure therapy (Difede, 2014). The pilot trial was randomized, placebo-controlled, and double-blind and found significantly greater PTSD remission rates for DCS group, with larger between groups effect sizes (Difede, 2014). Understanding the processes of reconsolidation and the crucial role synaptic plasticity plays in fear conditioning does have exciting and important implication for psychopathology specifically PTSD. There are still barriers and boundary conditions to be understood and overcome for example, memory age and strength. In Posttraumatic stress disorder, unwanted memories need to be retrieved and destabilized before they can be modified during reconsolidation. One of the barriers particular to PTSD is that researchers have proposed that younger and weaker memories are more likely to be modified after reconsolidation than older and stronger memories which are less likely to be modified (Wihchet, 2011). Further boundary conditions highlighted by Shwabe at al (2014) is the context in which the reactivation takes place, and the presence of new information at reactivation of the memories. Therefore, more research is needed to understand exactly when memories do and do not undergo reconsolidation in order to use reconsolidation as a treatment for disorders such as PTSD.

Music Appreciation Text Questions Essay

Please complete the following questions. It is important that you use full sentences and present the questions and answers when you submit your work. Submit the work as a file attachment. This means you complete all work in a word processing document (e.g., Microsoft Word) and attach the file using the dropbox tool. Use the Unit 3: Text Questions dropbox basket. The answers to the Review & Critical Thinking questions are worth 10 points. Review Questions 1. What is the Hurrian song? Why is it important?The Hurrian Song is a collection of music inscribed on cuneiform on clay tablets. Its important because it is one of the first times Hymns were written down. 2. What is the Natya Shastra? Why is it important? Natya Shastra is a writing on the performing arts, dancing, and stage performance. This is important because it gives quite a detailed information on the types of instruments that was used at the time and was popular. 3. Who were troubadours? What was their music like?Troubadours were traveling poet musicians who traveled from place to place singing and performing for the nobility. The songs that were sang were generally monophic and they often accompanied themselves with an instrument like a lyre or even a drum. 4. What are modes? Describe at least one type of mode. Modes were used before the modern day scales. One Kind of mode is Ionian. 5. What is polyphonic music? How does it differ from monophonic music?Polyphonic Music uses two or more independent melodies. It differs from monophic music because monophic music was dominated in early middle ages. Critical Thinking Questions 1. Why did early humans develop music? What are some of the ways that they were thought to create music?Early Humans developed music because they wanted to express themselves. One way they were thought to create music was by listening to natural sounds and repeating them. 2. Why is the study of prehistoric and ancient music important? What can we learn from it?The study of prehistoric/ancient music is important because you can see how music  started and how it advanced. We can learn how they lived back then from it. 3. What roles did music play in the life of prehistoric and ancient people? Are the roles similar to or different from the roles that it plays today?Are the roles similar to or different from the roles that it plays today? The role music played was entertainment and Religious support. The roles are similar today its just more diverse. Discussion Questions Please post questions and answers on the UNIT THREE discussion boards. Unless otherwise instructed, you should submit at least one full paragraph for each question. Each discussion assignment is worth 5 points.

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Societal Boundaries in Kate Chopins The Story of an Hour...

Societal Boundaries in Kate Chopins The Story of an Hour and Desirees Baby As humans, we live our life within the boundaries of our belief systems and moral guidelines we were raised with. Kate Chopin’s â€Å"The Story of an Hour† and â€Å"Desiree’s Baby† tells the story of two women who live according to those societal boundaries. American author Kate Chopin (1850–1904) wrote about a hundred short stories and two novels in the 1890s. Most of her fiction is set in Louisiana and most of her best-known work focuses on the lives of sensitive, intelligent women. After her fathers death, Kates family included her widowed mother, her widowed grandmother and her widowed great-grandmother.†¦show more content†¦Themes as self-reliant women as protagonists, post Civil War racism, male/female relationships and what would eventually become known as male chauvinism are common. These were difficult times for many women because of the domination of men over them. A woman was expected to act and behave in ways tha t were submissive to men in every aspect of their life. Indeed, a woman’s life revolved around her husband and his needs and desires. Women had very little say in their own ambitions or desires. Behaving in non-conventional ways would mean being shunned from society. However, one woman’s world revolves around and for her husband while another dreams of a life free of marital boundaries. Nevertheless, Kate Chopin uses two types of irony in â€Å"The Story of an Hour† to reflect her views. Situational irony refers to the opposite of what is supposed to happen, and dramatic irony occurs when the reader knows something that the rest of the characters in the story do not know. The irony in this short story makes the reader understand that the unexpected happens in life. The first irony detected is in the way that Louise reacts to the news of the death of her husband, Brently Mallard. â€Å"She did not hear the story as many women have heard the same, with a paralyzed inability to accept its significance†. Instead, she acceptsShow MoreRelatedAn Analysis Of Kate Chopin s Chopin 1690 Words   |  7 PagesKate Chopin was a famous American author of many short stories and novels. Chopin is now considered to have been a predecessor of the feminist movement and a leader of the feminist authors of the late 19th and early 20th centuries. Kate Chopin lived a rather traditional life as a housewife until her husband’s untimely death, which significantly changed the course of her life. Chopin s career as a writer actually began when she started facing financial struggles due to the death of her husband. Chopin’s

Demand And Supply Of The International Business...

Chapter 7: 1. Exporters typically prefer conservative measures when managing foreign receivables. Because of this, there is a tendency to lean on the side of caution. Describe at least three reasons for this conservativism. Exporters typically prefer conservative measures when managing foreign receivables. Because of this, there is a tendency to lean on the side of caution. Three reasons for this conservatism are described below: 1. Fluctuation in exchange rates: Exchange rates of currencies of different countries fluctuate continuously and in a very random manner with the change in the demand and supply state of the concerned currency. That can translate the profit from the international business transaction into a loss or vice-versa. Thus, the exporters dealing with foreign receivables should be conservative to avoid this risk. 2. The difference in the legal system: Different countries have different legal rules and policies for dealing with and managing the foreign accounts receivable. It is mostly harder for a business to pursue any overdue amounts from an international business due to the difference in the legal system. It is another reason for the conservative approaches of the exporters. 3. Change in export prices: Unexpected change in the commodity prices in a particular country will arise a great risk for the exporters when managing foreign receivables. Change in commodity price will also influence various other costs associated with the export likeShow MoreRelatedFunctions Of Foreign Exchange Markets Essay1656 Words   |  7 PagesWhen different countries enter business together there must be currency conversion, foreign exchange markets exist because there is need to move these currencies around (Murray, Ju, Gao, 2012).. Foreign exchange market is where currencies are traded (worldbank.org). 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Displaced People Free Essays

Myanmar is a country located in Central Asia that has experienced massive refugee migration in the last two decades. The displacement of Myanmar nationals, specifically the Rohingya Muslim group, is mainly due to three factors. Firstly, these residents have fled to other countries and even continents in order to avoid further conflict within the state (UNHCR 213). We will write a custom essay sample on Displaced People or any similar topic only for you Order Now The nature of conflict is based on human rights abuses, while others are centered on religious differences. It should be understood that Myanmar has been mainly run by the military for at least 30 years and any rebellious acts against these forces immediately result in massive killings and other forms of persecution (UNHCR 59). In addition, the principles and beliefs of the Muslim Rohingya group are largely different from that of the military. Thus, to these refugees, migration appears to be the only solution for safety and ultimately, survival. There are reports that describe entire villages burned down by highly aggressive members of the military. Two of the most documented villages in Myanmar that have experienced massive migration are the Kanyi and Karen villages. The closest country to Myanmar is Thailand and thus this neighboring country has seen a great influx of refugees in the last few decades. Thailand has been very supportive to displaced Myanmar nationals as they fully assist in providing shelter to these helpless individuals. Unfortunately, refugees from Myanmar often reach Thailand in a very deplorable state, as they have traveled by foot or by sea for several days or weeks to simply cross the border. To date, there are approximately 200,000 Myanmar refugees who currently reside in camps around Thailand, with most of them having settled there almost 20 years ago. Other Myanmar refugees have moved to Bangladesh for temporary shelter, as there were particular groups in this country that has close linguistic ties with Myanmar. By the 1990’s, approximately 270,000 refugees have been documented to move out of the northern state of Rakhine in Myanmar and were directed to two Bangladeshi refugee camps, namely Nayapara and Kutupalong. The current government of Myanmar has earlier expressed their refusal to include the Rohingya group as their citizens and would only recognize this as an ethnic group. Fifteen years later, most of the Rohingya refugees have returned to Myanmar, yet a small portion of this population made up of around 26,000 refugees have continued to refuse to return to their home country. Since Bangladesh is also a developing country, the exile of these Myanmar citizens was not as simple as could be imagined. These refugees had to adapt to their new environment for the next 15 years and eventually, through the help of the United Nations High Commissioner for Refugees, these individuals were transferred to Ontario, Canada. Other Myanmar refugees have also been reported in Malaysia, Indonesia, The Philippines and the United States. Another reason for displacement of Rohingya Muslims is political, wherein this indigenous group was poorly treated simply for the reason that they have are considered to have no social status in Myanmar. The military government considers this group at stateless and that they have no capacity to pay for the issuance of Myanmar identification cards, which is the requirement for citizenship in the country. Another cause for displacement of Myanmar nationals is environmental disaster, such as the tsunami that was generated after an earthquake that occurred in the Pacific Ocean in 2004 (UNHCR 11). The strong waves emanating from the earthquake resulted in a tsunami that left Myanmar, India, Indonesia and other Southeast Asian countries under water for several months. Myanmar residents were thus pushed to move to higher ground and farther from the sea, in order to avoid any additional effects that may come after that strong earthquake. The tsunami of 2004 has resulted in the migration of the Myanmar nationals to neighboring countries such as Thailand, Bangladesh and Malaysia. How to cite Displaced People, Papers

Concept of Project Management Methodology-Myassignmenthlep.cm

Question: Discuss about the Concept of Project Management. Answer: Introduction The main objective of the literature review is To understand the concept of project management methodology for software development project. It will allow the reader to gain deeper understanding about the project management methodologies. The benefits and limitations of the methods can be studied and the most appropriate method for the software development project should be selected. The information has been collected from various sources such as books, articles, journals, online publications and previous research papers. As per Glaiel, Moulton and Madnick, 2014, Software development project consist of many integrated and functionally dependent activities which combines to form a new product. Software projects develop a product which has never been tested. The scope of the project changes many times which leads to delays and extended budgets. Furthermore, lack of communication between the management and software developers affects the deliverables and final outcome of the project (Heagney, 2016). The literature will be useful in selecting the framework which will provide a structured approach to achieve all the objectives of the project. The methodologies which can be used are: Agile methodology Agile is commonly used for software and IT projects. According to Glaiel, Moulton and Madnick, 2014, More than 35% of project manager have adopted agile in IT related projects due to its incremental model. There are four values which are included in Agile: interactions of individuals, working software, collaboration of customer and adapting to the change. As per to Moniruzzaman and Hossain, 2013, Agile methodology should be used is projects which are not well defined. It is suitable for projects which b involves human interactions and collection of data. It allows the manager to develop self managed teams which performs their task in an effective manner. The main benefits of adoption of Agile method is that it allows the manger to make changes as per the requirements of the project. The inputs and feedback is taken from the stakeholders and it is included in the process. Azim, et.al, 2016 suggests that Agile is useful where there is need for drastic shifts or change in the assignme nts of the team. It also ensures that each process is reviewed and tested before its launch. On the contrary, Morley, 2016 believes that It becomes difficult to assess the requirements and efforts in lager IT projects and its deliverables. It can be used only with smaller IT projects. Similarly, Nelson and Morris, 2014 pints out that, Agile lacks effective designing and documentation stages which can affect the performance of the project. Project management body of knowledge (PMBOK) Project management body of knowledge (PMBOK) is a traditional method which is generic in nature. It focuses on estimations of work, risk identification, dependencies, time scales and handling of different activities. It has various best practice principles which can be used to successfully complete the project. It includes 39 groups with 9 knowledge aspects (Banihashemi, Hosseini, and Sankaran, 2017). The areas of knowledge include time, cost, integration, scope, communication, quality risk, human resources and procurement. Along with this, The process of PMBOK consists of initiation, creation of plans, implementation, reviewing and monitoring, controlling and project closure. It provides resources to the manager which helps him to gain understanding about the requirements of the project. According to Nelson and Morris, 2014, PMBOK uses iterative environment and it is completely based on the requirements of the customers. On the contrary, Rahmanian, 2014 believes that PMBOK can incr ease rigidity in IT projects as it encompasses extra when applied. It considers the entire project as a single identity which increases complexities for the manger. Furthermore, it uses descriptive approach including governance thorough project sponsor and stakeholder which may not be suitable for the IT related projects (Bresnen, 2016). Software development project can be benefitted Due To This Approach Because It Allows Error Free Updating. Prince 2 PRINCE 2 provides a systematic and structured approach which allows the project manager to organize and control different activities in the project. It has 44 process groups which helps interaction between various activities. It can be easily integrated with different models such as ITIL, managing successful programs, OGC gateway and CMMI. Furthermore, it identifies the key risk areas in the project which can be used to reduce complexities in the entire project. As per the Turner, 2016, PRINCE 2 differentiates the roles of project manager and workers which helps in managing all the activities. It is completely a process driven methodology which can be useful for software development project. On the contrary, Banihashemi, Hosseini, and Sankaran, 2017 believes that PRINCE 2 is not appropriate for the iterative approach of development. It is completely different from PMBOK as it does not contain knowledge areas and processes. IPMA Competence baseline According to Leach, 2014, IPMA Competence baseline is a model which uses competencies, qualification, knowledge and experience of the project manager to attain the objectives. The project manager can develop his own practices which can be applied to the project. It can be useful in defining competencies such as contextual, technical and behavioral. Moniruzzaman and Hossain, 2013 states that ICB method is completely different from other methodologies because it allows the person to develop appropriate methods and techniques. It can be useful for the project because the project manager has through knowledge about the concerned project. But Glaiel, Moulton and Madnick, 2014 argues that ICB does not provide any specific approach or methods which should be applied to the project. Waterfall methodology Waterfall methodology is known for its linear sequential and life cycle based model. It require through analysis and planning at each stage. The requirements are defined in the initial stages which help in planning and creation of standards. It has many steps which consist of planning, development, quality assurance, monitoring and project completion. It follows a sequential process which ensures that all the deliverables are produced with high quality. Only after the analysis the next phase is started. As pe Rahmanian, 2014, Waterfall method should be used for software testing due to its systematic approach. It should be applied to those projects which has clear and well defined requirements. Banihashemi, Hosseini, and Sankaran, 2017 states that Waterfall method allows the manger to follow the schedules which does not overlapping of activities. But it does not allow customer interaction which is needed is software projects. Morley, 2016 argues that It is not possible to back and mak e changes in the plan which increases rigidity in the project. Software projects range from moderate to high risk. Waterfall method will not be suitable for this. It is successful where technology is clearly understood and less ambiguity is there. Apart from this, the cost of fixing the errors can be very costly for the manger which can cause delays. Scrum methodology Scrum methodology provides a framework to the manager which makes it easy to manage complex activities involved in the project. It was developed as a software development project. But now it is also used in new product development and innovative projects. It can be useful in quick development and testing of codes. According to Glaiel, Moulton and Madnick, 2014Scrum considers the feedback of the customers which allows it to make changes as per the requirements. Changes can be easily made which improves the performance of the project. Apart from this, it can be used with different technologies, systems and programming language. It not only improves the quality of the deliverables but also allows the manger to follow the schedules. But Walker, 2015 believes that Scrum can lead to scope creep situation because it does not have end date. It will encourage the stakeholders to demand more improvement and development is the existing system. It may not be possible for the manager to achieve this aspect of the project. Similarly, lack of commitment and support of the workers will result in failure of the entire project (Gollenia, 2016). IT should be only used when trust and collaboration exist between team members and the project manager. Conclusion The most appropriate method which should be applied to Software development project is Agile methodology. It will allow the project manager to bring relevant changes at very low cost. Agile model uses incremental approach which is produced at regular intervals. It does not require through planning which is needed in Waterfall method in the initial stages. The project manager of the Software development project can customize the process as per his requirement. It is not possible in PMBOK which increases rigidity in the process. Along with this, it does not rely on the knowledge and experience of the project manager which is used by IPMA Competence baseline method. Therefore, it will be beneficial for the project manager to use Agile methodology in the Software development project. It will have long term benefits which will improve the performance of the project. References Azim, N., et.al, 2016. People Factors in Agile Software Development and Project Management.International Journal of Emerging Technology in Computer Science Electronics (IJETCSE) ISSN, 0976-1353. Banihashemi, S., Hosseini, M.R., Golizadeh, H. and Sankaran, S., 2017. Critical success factors (CSFs) for integration of sustainability into construction project management practices in developing countries. International Journal of Project Management. Bresnen, M. (2016). Institutional development, divergence and change in the discipline of project management.International journal of project management,34(2), 328-338. Glaiel, F.S., Moulton, A. and Madnick, S.E., 2014. Agile project dynamics: A system dynamics investigation of agile software development methods. Gollenia, L.A., 2016. Business Transformation Management Methodology. Routledge. Heagney, J., 2016. Fundamentals of project management. AMACOM Div American Mgmt Assn. Heagney, J., 2016. Fundamentals of project management. AMACOM Div American Mgmt Assn. Konstantinou, E. and Mller, R., 2016. The role of philosophy in project management. Project Management Journal, 47(3), pp.3-11 Leach, L.P., 2014. Critical chain project management. Artech House Moniruzzaman, A.B.M. and Hossain, D.S.A., 2013. Comparative study on agile software development methodologies. arXiv preprint arXiv:1307.3356. Morley, C., 2016. Management d'un projet systme d'Information-8e d.: Principes, techniques, mise en oeuvre et outils. Dunod. Nelson, R.R. and Morris, M.G., 2014. IT Project Estimation: Contemporary Practices and Management Guidelines. MIS Quarterly Executive, 13(1). Rahmanian, M., 2014. A comparative study on hybrid IT project management. International Journal of Computer and Information Technology, 3(05), pp.1096-1099. Turner, R., 2016. Gower handbook of project management. Routledge. Walker, A., 2015. Project management in construction. John Wiley Sons.